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Effect of glycerol on GHR and IGF-1 gene expression in breast muscle and on growth of Japanese meat quails.
Silva, S C C; Gasparino, E; Voltolini, D M; Pires, A V; Tanamati, F; Garcia, A L S; de Oliveira, D P.
Afiliación
  • Silva SC; Programa de Pós-Graduação em Zootecnia, Universidade Estadual de Maringá stefania_caroline@hotmail.com.
Genet Mol Res ; 12(3): 3856-61, 2013 Sep 23.
Article en En | MEDLINE | ID: mdl-24085446
We evaluated messenger RNA (mRNA) expression of the growth-hormone (GHR) and insulin-like growth factor (IGF-1) genes in 28-day-old Japanese meat quails fed diets containing 0, 8, or 12% dietary glycerol in substitution of corn. Total RNA was extracted from the breast muscle and the DNA was amplified with specific primers using real-time PCR. Feed conversion ratio and feed intake were evaluated. The birds fed 8 and 12% glycerol presented higher IGF-1 mRNA expression [0.059 and 0.049 arbitrary units (AU), respectively] relative to those not fed with glycerol (0.029 AU), while 12% glycerol reduced GHR mRNA expression (0.022 AU). Dietary inclusion of 8% glycerol promoted similar performance results (feed conversion) as the diet with no glycerol. We conclude that inclusion of glycerol in the diet affects GHR and IGF-1 gene expression in Japanese meat quails. However, considering the performance results and the expression of the GHR and IGF-1 genes, 8% glycerol may be safely included in the diet of meat quails.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Hormona del Crecimiento / Expresión Génica / Glicerol / Carne Límite: Animals Idioma: En Revista: Genet Mol Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2013 Tipo del documento: Article Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor I del Crecimiento Similar a la Insulina / Hormona del Crecimiento / Expresión Génica / Glicerol / Carne Límite: Animals Idioma: En Revista: Genet Mol Res Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2013 Tipo del documento: Article Pais de publicación: Brasil