Five novel naphthylisoquinoline alkaloids with growth inhibitory activities against human leukemia cells HL-60, K562 and U937 from stems and leaves of Ancistrocladus tectorius.

Jiang, Chao; Li, Zhan-Lin; Gong, Ping; Kang, Sheng-Li; Liu, Ming-Sheng; Pei, Yue-Hu; Jing, Yong-Kui; Hua, Hui-Ming

Jiang, Chao; Li, Zhan-Lin; Gong, Ping; Kang, Sheng-Li; Liu, Ming-Sheng; Pei, Yue-Hu; Jing, Yong-Kui; Hua, Hui-Ming.

Afiliación

Jiang C; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Li ZL; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Gong P; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; School of Life Science & Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Kang SL; Department of Pharmacy, Hainan Medical College, Haikou 571101, PR China.
Liu MS; Department of Pharmacy, Hainan Medical College, Haikou 571101, PR China.
Pei YH; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
Jing YK; Mount Sinai School of Medicine, New York, NY 10029, USA.
Hua HM; Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, PR China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China. Electronic address: huimhua@163.com.

Fitoterapia ; 91: 305-312, 2013 Dec.

Article en En | MEDLINE | ID: mdl-24076380

Asunto(s)

Isoquinolinas/aislamiento & purificación; Leucemia/tratamiento farmacológico; Magnoliopsida/química; Naftoles/uso terapéutico; Antineoplásicos Fitogénicos/química; Antineoplásicos Fitogénicos/aislamiento & purificación; Antineoplásicos Fitogénicos/farmacología; Antineoplásicos Fitogénicos/uso terapéutico; Células HL-60; Humanos; Concentración 50 Inhibidora; Isoquinolinas/química; Isoquinolinas/farmacología; Células K562; Estructura Molecular; Naftoles/química; Naftoles/aislamiento & purificación; Naftoles/farmacología; Fitoterapia; Extractos Vegetales/química; Extractos Vegetales/farmacología; Extractos Vegetales/uso terapéutico; Hojas de la Planta/química; Tallos de la Planta/química; Células U937

Palabras clave

7-Epi-ancistrobrevine D (PubChem CID 375950); Ancistrobertsonine B (PubChem CID 10646544); Ancistrocladaceae; Ancistrocladinine (PubChem CID 375959); Ancistrocladus tectorius; Ancistrotanzanine A (PubChem CID 10319100); Ancistrotanzanine B (PubChem CID 10002166); Ancistrotectoriline B (PubChem CID 10093654); Ancistrotectorine (PubChem CID 179169); Ancistrotectorine E; Ancistrotectorines A; Ancistrotectorines B; Ancistrotectorines C; Ancistrotectorines D; Growth inhibitory activity; Hamatine (PubChem CID 161741); Hamatinine (PubChem CID 628520); Naphthylisoquinoline alkaloid

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia / Magnoliopsida / Isoquinolinas / Naftoles Límite: Humans Idioma: En Revista: Fitoterapia Año: 2013 Tipo del documento: Article Pais de publicación: Países Bajos

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