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Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload.
Fisher-Wellman, Kelsey H; Gilliam, Laura A A; Lin, Chien-Te; Cathey, Brook L; Lark, Daniel S; Darrell Neufer, P.
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  • Fisher-Wellman KH; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Physiology, East Carolina University, Greenville, NC 27858, USA. Electronic address: k.fisher-wellman@garvan.org.au.
  • Gilliam LAA; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Physiology, East Carolina University, Greenville, NC 27858, USA.
  • Lin CT; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Physiology, East Carolina University, Greenville, NC 27858, USA.
  • Cathey BL; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Physiology, East Carolina University, Greenville, NC 27858, USA.
  • Lark DS; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Kinesiology, East Carolina University, Greenville, NC 27858, USA.
  • Darrell Neufer P; East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC 27858, USA; Department of Physiology, East Carolina University, Greenville, NC 27858, USA; Department of Kinesiology, East Carolina University, Greenville, NC 27858, USA.
Free Radic Biol Med ; 65: 1201-1208, 2013 Dec.
Article en En | MEDLINE | ID: mdl-24056031
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complejo Piruvato Deshidrogenasa / Superóxidos / Glutatión / Peróxido de Hidrógeno / Mitocondrias Musculares Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2013 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complejo Piruvato Deshidrogenasa / Superóxidos / Glutatión / Peróxido de Hidrógeno / Mitocondrias Musculares Tipo de estudio: Prognostic_studies Límite: Adult / Animals / Female / Humans / Male Idioma: En Revista: Free Radic Biol Med Asunto de la revista: BIOQUIMICA / MEDICINA Año: 2013 Tipo del documento: Article Pais de publicación: Estados Unidos