Simultaneous derivatization and air-assisted liquid-liquid microextraction of some parabens in personal care products and their determination by GC with flame ionization detection.
J Sep Sci
; 36(21-22): 3571-8, 2013 Nov.
Article
en En
| MEDLINE
| ID: mdl-24039137
A simultaneous derivatization/air-assisted liquid-liquid microextraction technique has been developed for the sample pretreatment of some parabens in aqueous samples. The analytes were derivatized and extracted simultaneously by a fast reaction/extraction with butylchloroformate (derivatization agent/extraction solvent) from the aqueous samples and then analyzed by GC with flame ionization detection. The effect of catalyst type and volume, derivatization agent/extraction solvent volume, ionic strength of aqueous solution, pH, numbers of extraction, aqueous sample volume, etc. on the method efficiency was investigated. Calibration graphs were linear in the range of 2-5000 µg/L with squared correlation coefficients >0.990. Enhancement factors and enrichment factors ranged from 1535 to 1941 and 268 to 343, respectively. Detection limits were obtained in the range of 0.41-0.62 µg/L. The RSDs for the extraction and determination of 250 µg/L of each paraben were <4.9% (n = 6). In this method, the derivatization agent and extraction solvent were the same and there is no need for a dispersive solvent, which is common in a traditional dispersive liquid-liquid microextraction technique. Furthermore, the sample preparation time is very short.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Parabenos
/
Aire
/
Microextracción en Fase Líquida
/
Preparaciones para el Cabello
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
J Sep Sci
Año:
2013
Tipo del documento:
Article
País de afiliación:
Irán
Pais de publicación:
Alemania