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Glycaemic control in children with neonatal diabetes and type 1 diabetes in Vietnam.
Tran, Fiona; Vu, Dung C; Nguyen, Hoan T; Bui, Thao P; Huynh, Loan T; Nguyen, Khanh P; Nguyen, Van T; Tran, Hiep M; Tran, Dong; Hoang, Thuy D; Harkin, Nuala; Armstrong, Kate; Jameson, Karen; Pham, Anna; Cowell, Chris T; Craig, Maria E.
Afiliación
  • Tran F; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, Australia.
Int Health ; 3(3): 188-92, 2011 Sep.
Article en En | MEDLINE | ID: mdl-24038369
Childhood diabetes care may be suboptimal in resource-poor countries. A cross-sectional study of youths with diabetes aged ≤19 years attending the three major paediatric centres in Vietnam was performed. Diabetes management was documented by questionnaire. Glycated haemoglobin (HbA1c) was measured with a fingerprick blood sample. Multiple linear regression analysis was used to examine factors associated with glycaemic control. In total, 105 patients participated, comprising 93 with type 1 diabetes and 12 with neonatal diabetes. The median age was 11.5 years [interquartile range (IQR) 6.4-14.5 years] and the median duration of diabetes was 2.6 years (IQR 1.5-6.1 years). Patients with type 1 diabetes performed few blood glucose tests per month (median 8, IQR 4-30). Mean HbA1c was higher in patients with type 1 diabetes compared with neonatal diabetes (9.9% vs. 7.5%; P = 0.01). In type 1 diabetes using multivariate analysis, higher HbA1c was associated with older age (ß = 0.3, 95% CI 0.2-0.4; P < 0.001), lower frequency of blood glucose monitoring (ß = -0.06, 95% CI -0.10 to 0.12; P = 0.01) and use of pre-mixed insulin (ß = -1.7, 95% CI -3.4 to 0.0; P = 0.05). In conclusion, international glycaemic control targets for childhood diabetes (HbA1c <7.5%) are not being achieved in Vietnam, and intensive diabetes management is rare. There is an urgent need to address barriers to achieving optimal control in this population.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Int Health Año: 2011 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Int Health Año: 2011 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido