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Use of quantitative microbial risk assessment when investigating foodborne illness outbreaks: the example of a monophasic Salmonella Typhimurium 4,5,12:i:- outbreak implicating beef burgers.
Guillier, Laurent; Danan, Corinne; Bergis, Hélène; Delignette-Muller, Marie-Laure; Granier, Sophie; Rudelle, Sylvie; Beaufort, Annie; Brisabois, Anne.
Afiliación
  • Guillier L; Laboratoire de sécurité des aliments, ANSES, F-94000, Maisons-Alfort, France. Electronic address: laurent.guillier@anses.fr.
Int J Food Microbiol ; 166(3): 471-8, 2013 Sep 16.
Article en En | MEDLINE | ID: mdl-24036262
A major community outbreak of salmonellosis occurred in France in October 2010. Classical epidemiological investigations led to the identification of beef burgers as the cause of the outbreak and the presence of the emerging monophasic Salmonella Typhimurium 4,5,12:i:-. The objective of this study was to understand the events that led to this large outbreak, that is to say, what are the contributing factors associated with consumer exposure to Salmonella. To this end, intensive microbiological investigations on several beef burgers were conducted and a risk assessment model was built. The microbiological results confirm the presence of Salmonella in all analysed frozen burgers at high levels of contamination above 1000 MPN/g. These results in frozen burgers combined with a model of thermal destruction were used to estimate the dose ingested by the exposed persons. Most people that consumed cooked beef burgers were exposed from 1.6 to 3.1 log10 (MPN). The number of sick people predicted with a dose-response relationship for Salmonella is consistent with the observed number of salmonellosis cases. The very high initial contamination level in frozen beef burgers is the primary cause of this large outbreak rather than bad cooking practices. Intensive investigations, modelling of the initial contamination and quantitative exposure and risk assessments are complementary to epidemiological investigation. They can be valuable elements for the assessment of missing information or the identification of the primary causes of outbreaks.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intoxicación Alimentaria por Salmonella / Salmonella typhimurium / Brotes de Enfermedades / Microbiología de Alimentos / Carne / Modelos Teóricos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: Europa Idioma: En Revista: Int J Food Microbiol Asunto de la revista: CIENCIAS DA NUTRICAO / MICROBIOLOGIA Año: 2013 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intoxicación Alimentaria por Salmonella / Salmonella typhimurium / Brotes de Enfermedades / Microbiología de Alimentos / Carne / Modelos Teóricos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: Europa Idioma: En Revista: Int J Food Microbiol Asunto de la revista: CIENCIAS DA NUTRICAO / MICROBIOLOGIA Año: 2013 Tipo del documento: Article Pais de publicación: Países Bajos