[The mechanism of the antitumor effect of total/subtotal radiotherapy with non-tumoricidal doses of radiation].

Shutko, A N; Akushevich, I V; Ekimova, L P; Mus, V F; Sokurenko, B P; Iurkova, L E; Matiurin, K S

Shutko, A N; Akushevich, I V; Ekimova, L P; Mus, V F; Sokurenko, B P; Iurkova, L E; Matiurin, K S.

Vopr Onkol ; 59(4): 475-8, 2013.

Article en Ru | MEDLINE | ID: mdl-24032222

RESUMEN

The myelodepression at therapy for solid malignancies is considered as a mediating element of common antineoplastic activity on the basis of ability of stem cells of hemapoietic system to participate in regeneration of the various tissues of the body, including tumor. The equivalence of the therapeutic benefit mediated by both mild myelodepression due to total/subtotal radiation exposure and conventional chemotherapy with cytotoxic drugs is argued.

Asunto(s)

Médula Ósea/efectos de la radiación; Radioisótopos de Cobalto/administración & dosificación; Radioisótopos de Cobalto/efectos adversos; Neoplasias/radioterapia; Antineoplásicos/uso terapéutico; Femenino; Humanos; Masculino; Neoplasias/tratamiento farmacológico; Dosificación Radioterapéutica; Estudios Retrospectivos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Médula Ósea / Radioisótopos de Cobalto / Neoplasias Tipo de estudio: Observational_studies Límite: Female / Humans / Male Idioma: Ru Revista: Vopr Onkol Año: 2013 Tipo del documento: Article Pais de publicación: Rusia

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