Challenges in the characterization of plasma-processed three-dimensional polymeric scaffolds for biomedical applications.
ACS Appl Mater Interfaces
; 5(19): 9312-21, 2013 Oct 09.
Article
en En
| MEDLINE
| ID: mdl-24028344
Low-temperature plasmas offer a versatile method for delivering tailored functionality to a range of materials. Despite the vast array of choices offered by plasma processing techniques, there remain a significant number of hurdles that must be overcome to allow this methodology to realize its full potential in the area of biocompatible materials. Challenges include issues associated with analytical characterization, material structure, plasma processing, and uniform composition following treatment. Specific examples and solutions are presented utilizing results from analyses of three-dimensional (3D) poly(ε-caprolactone) scaffolds treated with different plasma surface modification strategies that illustrate these challenges well. Notably, many of these strategies result in 3D scaffolds that are extremely hydrophilic and that enhance human Saos-2 osteoblast cell growth and proliferation, which are promising results for applications including tissue engineering and advanced biomedical devices.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poliésteres
/
Polímeros
/
Materiales Biocompatibles
/
Ingeniería de Tejidos
Límite:
Humans
Idioma:
En
Revista:
ACS Appl Mater Interfaces
Asunto de la revista:
BIOTECNOLOGIA
/
ENGENHARIA BIOMEDICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Estados Unidos