Antitumor and scavenging radicals activities of some polyphenols related to dehydroabietylamine derivatives.
J Asian Nat Prod Res
; 15(8): 819-27, 2013.
Article
en En
| MEDLINE
| ID: mdl-23952738
A novel series of polyphenols 4-9 were synthesized by the reaction of catechol with dehydroabietylamine derivatives. The antitumor activities of these compounds against L02 and HepG2 cells were investigated. Among them, compounds 4, 5, and 9 can inhibit HepG2 cells viability, but have lower inhibitory effect on L02 cells in the same concentration, indicating their potential for further development. Meanwhile, the novel series of polyphenols exhibited stronger radical-scavenging activities than the control groups.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Depuradores de Radicales Libres
/
Diterpenos
/
Polifenoles
/
Antineoplásicos
/
Antioxidantes
Límite:
Humans
Idioma:
En
Revista:
J Asian Nat Prod Res
Asunto de la revista:
BOTANICA
/
QUIMICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Reino Unido