Gold-catalyzed hydration of haloalkynes to α-halomethyl ketones.
J Org Chem
; 78(18): 9190-5, 2013 Sep 20.
Article
en En
| MEDLINE
| ID: mdl-23952293
A general atom-economical approach for the synthesis of α-halomethyl ketones is demonstrated through hydration of a wide range of haloalkynes. Other outstanding features include excellent yields from both alkyl- and aryl-substituted haloalkynes and wide functional group tolerance. This protocol is an alternative to conventional α-halogenation of ketones.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Alquinos
/
Compuestos Orgánicos de Oro
/
Hidrocarburos Halogenados
/
Cetonas
Idioma:
En
Revista:
J Org Chem
Año:
2013
Tipo del documento:
Article
Pais de publicación:
Estados Unidos