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The immunological profile of tumor-bearing animals determines the outcome of cancer immunotherapy.
Quetglas, José I; Hervas-Stubbs, Sandra; Smerdou, Cristian.
Afiliación
  • Quetglas JI; Division of Hepatology and Gene Therapy; Center for Applied Medical Research (CIMA); University of Navarra; Pamplona, Navarra, Spain.
Oncoimmunology ; 2(6): e24499, 2013 Jun 01.
Article en En | MEDLINE | ID: mdl-23894709
Do cancer patients responding to immunotherapy have immunological profiles that influence the therapeutic outcome, or do they develop efficient antitumor responses only upon immunotherapy? We came across this "chicken or the egg" dilemma when treating secondary liver tumors with Semliki Forest viruses expressing interleukin-12. In our system, the "egg," that is, the pre-treatment immunological profile, seemed to make the difference. The properties of an effective antitumor response were also defined.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oncoimmunology Año: 2013 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Oncoimmunology Año: 2013 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos