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A triggered DNA hydrogel cover to envelop and release single cells.
Jin, Juan; Xing, Yongzheng; Xi, Yanli; Liu, Xueli; Zhou, Tao; Ma, Xinxin; Yang, Zhongqiang; Wang, Shutao; Liu, Dongsheng.
Afiliación
  • Jin J; Key Laboratory of Organic Optoelectrics & Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China, Fax: +86-10-62796082; National Center for Nanoscience and Technology, Beijing 100190, P. R. China; University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Adv Mater ; 25(34): 4714-7, 2013 Sep 14.
Article en En | MEDLINE | ID: mdl-23836697
We develop an enzyme-triggered permeable DNA hydrogel cover to envelop and release single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and waste to pass through, leading to a cell viability as high as 98%. The design provides a general method to culture, monitor, and manipulate single cells, and has potential applications in cell patterning and studying cell communication.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Hidrogel de Polietilenoglicol-Dimetacrilato Límite: Animals Idioma: En Revista: Adv Mater Asunto de la revista: BIOFISICA / QUIMICA Año: 2013 Tipo del documento: Article Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ADN / Hidrogel de Polietilenoglicol-Dimetacrilato Límite: Animals Idioma: En Revista: Adv Mater Asunto de la revista: BIOFISICA / QUIMICA Año: 2013 Tipo del documento: Article Pais de publicación: Alemania