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Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102.
Quan, Lin-Hu; Piao, Jin-Ying; Min, Jin-Woo; Kim, Ho-Bin; Kim, Sang-Rae; Yang, Dong-Uk; Yang, Deok Chun.
Afiliación
  • Quan LH; Korean Ginseng Center Most Valuable Product and Ginseng Genetic Resource Bank, Kyung Hee University, Yongin 446-701, Korea.
J Ginseng Res ; 35(3): 344-51, 2011 Sep.
Article en En | MEDLINE | ID: mdl-23717079
Ginsenoside Rb1is the main component in ginsenosides. It is a protopanaxadiol-type ginsenoside that has a dammarane-type triterpenoid as an aglycone. In this study, ginsenoside Rb1 was transformed into gypenoside XVII, ginsenoside Rd, ginsenoside F2 and compound K by glycosidase from Leuconostoc mesenteroides DC102. The optimum time for the conversion was about 72 h at a constant pH of 6.0 to 8.0 and the optimum temperature was about 30℃. Under optimal conditions, ginsenoside Rb1 was decomposed and converted into compound K by 72 h post-reaction (99%). The enzymatic reaction was analyzed by highperformance liquid chromatography, suggesting the transformation pathway: ginsenoside Rb1→ gypenoside XVII and ginsenoside Rd→ginsenoside F2→compound K.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Ginseng Res Año: 2011 Tipo del documento: Article Pais de publicación: Corea del Sur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Ginseng Res Año: 2011 Tipo del documento: Article Pais de publicación: Corea del Sur