Your browser doesn't support javascript.
loading
Administration of intravenous iron complexes on implantable central venous access port in cancer patients in France: the FERPAC survey.
Janus, Nicolas; Scotte, Florian; Rey, Jean-Baptiste; Amet, Sabine; Rouillon, Laurence; Zakin, Lorraine; Mahi, Lamine; Deray, Gilbert; Launay-Vacher, Vincent.
Afiliación
  • Janus N; Service ICAR, Department of Nephrology, Groupe Hospitalier Pitié-Salpétrière, 47-83 Boulevard de l'Hôpital, 75013, Paris, France, nicolas.janus@psl.aphp.fr.
Support Care Cancer ; 21(10): 2743-8, 2013 Oct.
Article en En | MEDLINE | ID: mdl-23715817
PURPOSE: Implantable central venous access port (portacath) is used to provide long-term venous access and to deliver chemotherapy in cancer patients. Intravenous iron complexes are frequently prescribed in this setting, and some physicians use a portacath for their administration. The aim of this survey was to assess the frequency of this practice and the reasons supporting it. METHODS: This declarative survey was conducted in France; 497 oncologists/hematologists were contacted to answer a survey on their practices regarding the administration of intravenous iron via a portacath. RESULTS: A total of 141 recipients (29.5 %) completed the questionnaire. The intravenous iron complexes most frequently used were iron sucrose and ferric carboxymaltose, and 55.2 % of the responders reported using a portacath to administer intravenous iron complexes. The main reasons mentioned for this practice were ease of administration (27.9 %) and preservation of venous capital (27.6 %). The main reasons reported for not using a portacath to administer intravenous iron were a history of thrombosis (45.1 %) or potential drug interactions (17.7 %). Efficacy and safety were expected to be similar to those observed with peripheral administration. A 47.6 % of physicians declared that they usually did not observe adverse reactions after use of a portacath for iron administration. Intravenous iron administration was always planned after chemotherapy for 46.6 % of the responders and before chemotherapy for 38.2 %, whereas 15.3 % did not have any preference for either option. CONCLUSIONS: Intravenous iron complexes (mainly iron sucrose and ferric carboxymaltose) are commonly administered through a portacath in cancer patients in France. The choice for this route of administration is supported by clinical considerations, but further studies are needed to confirm the efficacy and safety of this practice.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Compuestos Férricos / Anemia Ferropénica / Catéteres Venosos Centrales / Ácido Glucárico / Maltosa / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Support Care Cancer Asunto de la revista: NEOPLASIAS / SERVICOS DE SAUDE Año: 2013 Tipo del documento: Article Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pautas de la Práctica en Medicina / Compuestos Férricos / Anemia Ferropénica / Catéteres Venosos Centrales / Ácido Glucárico / Maltosa / Neoplasias Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Support Care Cancer Asunto de la revista: NEOPLASIAS / SERVICOS DE SAUDE Año: 2013 Tipo del documento: Article Pais de publicación: Alemania