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Investigation of APOE isoforms and the association between APOE E3 and E4 with migraine in the Australian Caucasian population.
Stuart, Shani; Donges, Bianca; Murrell, Melanie; Haupt, Larisa M; Lea, Rod A; Griffiths, Lyn R.
Afiliación
  • Stuart S; School of Medical Science, Genomics Research Centre, Griffith Health Institute, Griffith University, Queensland, Australia.
Neuroreport ; 24(10): 499-503, 2013 Jul 10.
Article en En | MEDLINE | ID: mdl-23660682
Migraine is a debilitating neurovascular disease that is associated with pulsating head pain accompanied by nausea, vomiting, photophobia, phonophobia and sometimes visual sensory disturbances. Because of its role in nitric oxide regulation and interleukin release, apolipoprotein E (APOE) has been suggested to play a role in the migraine pathogenesis pathway. This study evaluated the potential role of three APOE variants in an Australian population and the role that they may play in susceptibility to migraine. The study found no significant association between the tested variants and migraine for any of the APOE variants investigated.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apolipoproteína E3 / Apolipoproteína E4 / Trastornos Migrañosos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Neuroreport Asunto de la revista: NEUROLOGIA Año: 2013 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Apolipoproteína E3 / Apolipoproteína E4 / Trastornos Migrañosos Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Oceania Idioma: En Revista: Neuroreport Asunto de la revista: NEUROLOGIA Año: 2013 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido