UDP-glucuronosyltransferase 2B15 (UGT2B15) is the major enzyme responsible for sipoglitazar glucuronidation in humans: retrospective identification of the UGT isoform by in vitro analysis and the effect of UGT2B15*2 mutation.

Nishihara, Mitsuhiro; Hiura, Yuto; Kawaguchi, Naohiro; Takahashi, Junzo; Asahi, Satoru

Nishihara, Mitsuhiro; Hiura, Yuto; Kawaguchi, Naohiro; Takahashi, Junzo; Asahi, Satoru.

Afiliación

Nishihara M; Drug Metabolism and Pharmacokinetics Research Laboratories, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited.

Drug Metab Pharmacokinet ; 28(6): 475-84, 2013.

Article en En | MEDLINE | ID: mdl-23648677

Asunto(s)

Glucuronosiltransferasa/metabolismo; Propionatos/metabolismo; Tiazoles/metabolismo; Genotipo; Glucuronosiltransferasa/genética; Humanos; Cinética; Oxazepam/metabolismo; Estudios Retrospectivos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Propionatos / Tiazoles / Glucuronosiltransferasa Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Drug Metab Pharmacokinet Asunto de la revista: FARMACOLOGIA / METABOLISMO Año: 2013 Tipo del documento: Article Pais de publicación: Reino Unido

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