Long-term in vivo effect of PEG bone tissue engineering scaffolds.

Engebretson, Brandon; Sikavitsas, Vassilios I

Engebretson, Brandon; Sikavitsas, Vassilios I.

Afiliación

Engebretson B; School of Chemical, Biological and Materials Engineering, The University of Oklahoma, Norman, OK 73019, USA.

J Long Term Eff Med Implants ; 22(3): 211-8, 2012.

Article en En | MEDLINE | ID: mdl-23582112

RESUMEN

Polyethylene glycol (PEG) performs multiple roles for bone tissue engineering scaffolds. Successful in vivo implantation for long periods of time requires a scaffold that is biocompatible, osteoconductive, osteoinductive, and promotes cell recruitment and attachment. PEG has significant advantages such as excellent biocompatibility and flexibility, but certain drawbacks such as poor mechanical strength and cell attachment limit its use as a plain scaffold. Instead, it is often used as an additive, composite, or delivery system. Below is a summary of current research involving the use of PEG-based biomaterials in bone tissue engineering, specifically with regard to long term in vivo effects.

Asunto(s)

Materiales Biocompatibles/química; Huesos; Polietilenglicoles/química; Ingeniería de Tejidos/métodos; Andamios del Tejido; Materiales Biocompatibles Revestidos; Humanos; Osteogénesis

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polietilenglicoles / Materiales Biocompatibles / Huesos / Ingeniería de Tejidos / Andamios del Tejido Límite: Humans Idioma: En Revista: J Long Term Eff Med Implants Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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