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Separation of piracetam derivatives on polysaccharide-based chiral stationary phases.
Kazoka, H; Koliskina, O; Veinberg, G; Vorona, M.
Afiliación
  • Kazoka H; Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, LV-1006, Riga, Latvia. helena@osi.lv
J Chromatogr A ; 1281: 160-5, 2013 Mar 15.
Article en En | MEDLINE | ID: mdl-23394745
High-performance liquid chromatography was used for the enantiomeric separation of two chiral piracetam derivatives. The suitability of six commercially available polysaccharide-based chiral stationary phases (CSPs) under normal phase mode for direct enantioseparation has been investigated. The influence of the CSPs as well the nature and content of an alcoholic modifier in the mobile phase on separation and elution order was studied. It was established that CSP Lux Amylose-2 shows high chiral recognition ability towards 4-phenylsubstituted piracetam derivatives.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piracetam / Polisacáridos / Cromatografía Líquida de Alta Presión Idioma: En Revista: J Chromatogr A Año: 2013 Tipo del documento: Article País de afiliación: Letonia Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piracetam / Polisacáridos / Cromatografía Líquida de Alta Presión Idioma: En Revista: J Chromatogr A Año: 2013 Tipo del documento: Article País de afiliación: Letonia Pais de publicación: Países Bajos