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Age-dependent pupillary light reflex parameters in children.
Daluwatte, Chathuri; Miles, Judith H; Christ, Shawn E; Beversdorf, David Q; Lofgreen, Andrew; Berliner, Nathan; Yao, Gang.
Afiliación
  • Daluwatte C; Department of Biological Engineering, University of Missouri, Columbia, MO 65211, USA.cldc82@mail.missouri.edu
Article en En | MEDLINE | ID: mdl-23366750
Pupillary light reflex (PLR) refers to the phenomenon where pupil size changes in response to stimulation with a flash of light. It is a simple functional test that can reveal dysfunctions associated with the PLR pathway. Although abnormal PLR responses have been reported in many neurological disorders, few studies investigated neurodevelopmental effects on PLR parameters. We studied the effect of age on PLR in a group of 6 to 17 year old children with typical development. A significant and consistent age effect was found on PLR latency in children younger than 10 years old. Age effects were also observed in resting pupil diameter and constriction amplitude. However such age related trends were not observed in children with neurodevelopment disorders. These results suggest that PLR has the potential to be used as a simple noninvasive tool for monitoring neurodevelopment in children.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reflejo Pupilar / Envejecimiento / Luz Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Annu Int Conf IEEE Eng Med Biol Soc Año: 2012 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Reflejo Pupilar / Envejecimiento / Luz Límite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Annu Int Conf IEEE Eng Med Biol Soc Año: 2012 Tipo del documento: Article Pais de publicación: Estados Unidos