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Recent developments in human immunodeficiency virus-1 latency research.
Chan, Chi Ngai; Dietrich, Isabelle; Hosie, Margaret J; Willett, Brian J.
Afiliación
  • Chan CN; MRC-University of Glasgow Centre for Virus Research, Bearsden Road, Glasgow G61 1QH, UK.
  • Dietrich I; MRC-University of Glasgow Centre for Virus Research, Bearsden Road, Glasgow G61 1QH, UK.
  • Hosie MJ; MRC-University of Glasgow Centre for Virus Research, Bearsden Road, Glasgow G61 1QH, UK.
  • Willett BJ; MRC-University of Glasgow Centre for Virus Research, Bearsden Road, Glasgow G61 1QH, UK.
J Gen Virol ; 94(Pt 5): 917-932, 2013 May.
Article en En | MEDLINE | ID: mdl-23364195
Almost 30 years after its initial discovery, infection with the human immunodeficiency virus-1 (HIV-1) remains incurable and the virus persists due to reservoirs of latently infected CD4(+) memory T-cells and sanctuary sites within the infected individual where drug penetration is poor. Reactivating latent viruses has been a key strategy to completely eliminate the virus from the host, but many difficulties and unanswered questions remain. In this review, the latest developments in HIV-persistence and latency research are presented.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Latencia del Virus / Fármacos Anti-VIH Límite: Humans Idioma: En Revista: J Gen Virol Año: 2013 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / VIH-1 / Latencia del Virus / Fármacos Anti-VIH Límite: Humans Idioma: En Revista: J Gen Virol Año: 2013 Tipo del documento: Article Pais de publicación: Reino Unido