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Modulation of neutrophil oxidative burst via histamine receptors.
Cíz, M; Lojek, A.
Afiliación
  • Cíz M; Department of Free Radical Pathophysiology, Institute of Biophysics, Academy of Sciences of the Czech Republic, Brno, Czech Republic. milanciz@ibp.cz
Br J Pharmacol ; 170(1): 17-22, 2013 Sep.
Article en En | MEDLINE | ID: mdl-23336732
Histamine has the ability to influence the activity of immune cells including neutrophils and plays a pivotal role in inflammatory processes, which are a complex network of cellular and humoral events. One of the main functions manifested by activated neutrophils is oxidative burst, which is linked to the production of reactive oxygen species; therefore, the effects of histamine receptor agonists and antagonists on the oxidative burst of neutrophils is reviewed. A role for the well-characterized histamine H1 and H2 receptors in this process is discussed and compared to that of the recently discovered H4 receptor.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Histamínicos / Agonistas de los Receptores Histamínicos / Receptores Acoplados a Proteínas G / Antagonistas de los Receptores Histamínicos Límite: Animals / Humans Idioma: En Revista: Br J Pharmacol Año: 2013 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Receptores Histamínicos / Agonistas de los Receptores Histamínicos / Receptores Acoplados a Proteínas G / Antagonistas de los Receptores Histamínicos Límite: Animals / Humans Idioma: En Revista: Br J Pharmacol Año: 2013 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Reino Unido