Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays.
J Clin Microbiol
; 51(4): 1244-6, 2013 Apr.
Article
en En
| MEDLINE
| ID: mdl-23325820
Evaluation of candidate antiviral drugs against Epstein-Barr virus (EBV), human herpesvirus 6 (HHV-6), and HHV-8 is hampered by the lack of convenient laboratory assays. We developed real-time quantitative PCR assays performed on supernatants of lymphoma cell lines and determined the 50% inhibitory concentrations (IC50s) of nucleoside, nucleotide, and pyrophosphate analogues against these herpesviruses.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antivirales
/
Herpesvirus Humano 6
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Herpesvirus Humano 4
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Herpesvirus Humano 8
/
Reacción en Cadena en Tiempo Real de la Polimerasa
Límite:
Humans
Idioma:
En
Revista:
J Clin Microbiol
Año:
2013
Tipo del documento:
Article
País de afiliación:
Canadá
Pais de publicación:
Estados Unidos