Bilateral choroidal neonatal neuroblastoma.

Cibis, G W; Freeman, A I; Pang, V; Roloson, G J; Case, W F; Ost, M; Huntrakoon, M; Rothberg, P G

Cibis, G W; Freeman, A I; Pang, V; Roloson, G J; Case, W F; Ost, M; Huntrakoon, M; Rothberg, P G.

Afiliación

Cibis GW; Children's Mercy Hospital, Section of Ophthalmology, Kansas City, Missouri.

Am J Ophthalmol ; 109(4): 445-9, 1990 Apr 15.

Article en En | MEDLINE | ID: mdl-2330947

RESUMEN

We treated a bilateral, well-differentiated neuroblastoma of the choroid in a patient who had congenital abdominal neuroblastoma. Although orbital metastasis of neuroblastoma is common, intraocular metastasis is not. In our patient, there was no amplification of the N-myc oncogene in the tumor of either eye. This is consistent with early-stage primary neuroblastoma. Histologically, the tumors were identical in each eye and well differentiated with Homer Wright rosettes; most neuroblastoma metastases have few rosettes and are composed of more undifferentiated, anaplastic cells. We believe that our patient had bilateral primary tumors and not metastatic tumors.

Asunto(s)

Neoplasias de la Coroides/secundario; Neoplasias Hepáticas/congénito; Neuroblastoma/congénito; Neoplasias de la Coroides/ultraestructura; Femenino; Humanos; Recién Nacido; Neuroblastoma/ultraestructura; Tomografía Computarizada por Rayos X

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Coroides / Neoplasias Hepáticas / Neuroblastoma Límite: Female / Humans / Newborn Idioma: En Revista: Am J Ophthalmol Año: 1990 Tipo del documento: Article Pais de publicación: Estados Unidos

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