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Recommendations on the use of everolimus in lung transplantation.
de Pablo, A; Santos, F; Solé, A; Borro, J M; Cifrian, J M; Laporta, R; Monforte, V; Román, A; de la Torre, M; Ussetti, P; Zurbano, F.
Afiliación
  • de Pablo A; University Hospital, Doce de Octubre, Madrid, Spain. alic1575@separ.es
Transplant Rev (Orlando) ; 27(1): 9-16, 2013 Jan.
Article en En | MEDLINE | ID: mdl-23276646
The antiproliferative effect of everolimus provides a therapeutic option in the immunosuppression therapy of lung transplantation, by reducing both the risk of acute rejection and the process of progressive fibrosis that determines chronic graft rejection. However, few data on the use of everolimus in lung transplantation have been published to date, and the specific indications of the drug, along with the most adequate time for its introduction or dosing, have not been defined yet. The aim of this article is to propose recommendations for the use of everolimus in lung transplant recipients, including indications, dosing schedules and the use of concomitant immunosuppression. This consensus document has been developed by experts of all the Spanish lung transplant groups from the review of the existing literature and the clinical experience.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Inmunosupresión / Trasplante de Pulmón / Sirolimus / Rechazo de Injerto Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Transplant Rev (Orlando) Asunto de la revista: TRANSPLANTE Año: 2013 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Inmunosupresión / Trasplante de Pulmón / Sirolimus / Rechazo de Injerto Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Transplant Rev (Orlando) Asunto de la revista: TRANSPLANTE Año: 2013 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos