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A novel synthetic compound, 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione, inhibits cisplatin-induced hearing loss by the suppression of reactive oxygen species: in vitro and in vivo study.
Shin, Y S; Song, S J; Kang, S U; Hwang, H S; Choi, J W; Lee, B H; Jung, Y-S; Kim, C-H.
Afiliación
  • Shin YS; Department of Otolaryngology, School of Medicine, Ajou University, Suwon, Republic of Korea; Center for Cell Death Regulating Biodrug, School of Medicine, Ajou University, Suwon, Republic of Korea.
  • Song SJ; Bio-organic Science Division, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, Republic of Korea.
  • Kang SU; Department of Otolaryngology, School of Medicine, Ajou University, Suwon, Republic of Korea; Center for Cell Death Regulating Biodrug, School of Medicine, Ajou University, Suwon, Republic of Korea.
  • Hwang HS; Department of Otolaryngology, School of Medicine, Ajou University, Suwon, Republic of Korea; Center for Cell Death Regulating Biodrug, School of Medicine, Ajou University, Suwon, Republic of Korea.
  • Choi JW; Department of Molecular Science & Technology, School of Medicine, Ajou University, Suwon, Republic of Korea.
  • Lee BH; Department of Otolaryngology, School of Medicine, Ajou University, Suwon, Republic of Korea; Center for Cell Death Regulating Biodrug, School of Medicine, Ajou University, Suwon, Republic of Korea.
  • Jung YS; Bio-organic Science Division, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, Republic of Korea.
  • Kim CH; Department of Otolaryngology, School of Medicine, Ajou University, Suwon, Republic of Korea; Center for Cell Death Regulating Biodrug, School of Medicine, Ajou University, Suwon, Republic of Korea. Electronic address: ostium@ajou.ac.kr.
Neuroscience ; 232: 1-12, 2013 Mar 01.
Article en En | MEDLINE | ID: mdl-23246618

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cisplatino / Especies Reactivas de Oxígeno / Quinolonas / Fármacos Neuroprotectores / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neuroscience Año: 2013 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cisplatino / Especies Reactivas de Oxígeno / Quinolonas / Fármacos Neuroprotectores / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neuroscience Año: 2013 Tipo del documento: Article Pais de publicación: Estados Unidos