Remarkable response to photodynamic therapy in residual T4N0M0 nasopharyngeal carcinoma: a case report.

Indrasari, S R; Timmermans, A J; Wildeman, M A; Karakullukcu, M B; Herdini, C; Hariwiyanto, B; Tan, I B

Indrasari, S R; Timmermans, A J; Wildeman, M A; Karakullukcu, M B; Herdini, C; Hariwiyanto, B; Tan, I B.

Afiliación

Indrasari SR; Department of Otorhinolaryngology, Gadjah Mada University, Yogyakarta, Indonesia.

Photodiagnosis Photodyn Ther ; 9(4): 319-20, 2012 Dec.

Article en En | MEDLINE | ID: mdl-23200012

RESUMEN

Local treatment of residual or recurrent nasopharyngeal carcinoma (NPC) is a challenge. Photodynamic therapy (PDT) is an established treatment modality for incurable head and neck carcinoma. Several studies reported induction of an immune response after PDT. We present a patient with residual T4N0M0 NPC who was treated with PDT for residual disease after initial treatment with neo-adjuvant chemotherapy and radiotherapy. Five years after PDT, the tumor did not progress and the patient is still in good condition. We discuss this remarkable long-term response to PDT and speculate on possible mechanisms.

Asunto(s)

Mesoporfirinas/uso terapéutico; Neoplasias Nasofaríngeas/tratamiento farmacológico; Fotoquimioterapia/métodos; Fármacos Fotosensibilizantes/uso terapéutico; Adulto; Carcinoma; Humanos; Masculino; Carcinoma Nasofaríngeo; Terapia Neoadyuvante; Neoplasia Residual/terapia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Neoplasias Nasofaríngeas / Fármacos Fotosensibilizantes / Mesoporfirinas Límite: Adult / Humans / Male Idioma: En Revista: Photodiagnosis Photodyn Ther Asunto de la revista: DIAGNOSTICO POR IMAGEM / TERAPEUTICA Año: 2012 Tipo del documento: Article País de afiliación: Indonesia Pais de publicación: Países Bajos

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