MRI signal changes in the skull base bone after endoscopic nasopharyngectomy for recurrent NPC: a serial study of 9 patients.
Eur J Radiol
; 82(2): 309-15, 2013 Feb.
Article
en En
| MEDLINE
| ID: mdl-23177186
PURPOSE: This study was focused on the serial changes in magnetic resonance images (MRI) of the skull-base bone that occur after endoscopic nasopharyngectomy in patients with local recurrent nasopharyngeal carcinoma (rNPC). MATERIALS AND METHODS: Nine patients with histologically proven rNPC were enrolled in this study. Two experienced radiologists independently reviewed all presurgical and postsurgical MR images for each patient. RESULTS: At 36 sites on the skull base, the MRI signal underwent a change after surgery, which took the form of a heterogeneous pattern of hypointense regions with moderate contrast enhancement on T1WI. The onset of changes ranged between 2 weeks and 3 months after surgery. For 21 of the sites, the changes subsided over the course of follow-up, while in 6 they remained stable. At 9 sites, the alteration MRI signal became more pronounced with time. Changes were more common on the homolateral side of the skull base with respect to the recurrent tumor (P<0.05). The skull-base bone adjacent to the resection boundary had a higher incidence of signal change than nonadjacent areas (P<0.05). CONCLUSIONS: MRI changes in the skull base bone, having a number of distinguishing characteristics, appear to be a common sequel to endoscopic nasopharyngectomy for rNPC.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Faringectomía
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Imagen por Resonancia Magnética
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Neoplasias Nasofaríngeas
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Neoplasias de la Base del Cráneo
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Recurrencia Local de Neoplasia
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur J Radiol
Año:
2013
Tipo del documento:
Article
Pais de publicación:
Irlanda