[Multiple endocrine neoplasia syndrome type 2].
Klin Khir
; (8): 55-7, 2012 Aug.
Article
en Uk
| MEDLINE
| ID: mdl-23113424
Multiple endocrine neoplasia (MEN) syndrome--is a hereditary disease which is characterized by synchronous or metachronous development of benign (adenoma, hyperplasia) or malignant tumors in the endocrine organs. The presence of medullary thyroid carcinoma and pheochromocytoma are mandatory requirements of MEN 2 syndrome. The purpose of our study was to perform timely diagnosis and optimal surgical treatment of patients with MEN 2 syndrome. Over the 1999-2009 years in the clinic we have diagnosed the MEN 2 syndrome in 5 patients, of whom two women were sisters. In all patients we observed medullary thyroid carcinoma and pheochromocytoma. Two patients had bilateral pheochromocytoma, and the clinical course was characterized with mild arterial hypertension. Primary hyperparathyroidism was observed in 2 patients. In the near relatives of patients with MEN 2 syndrome it must measure calcitonin, catecholamines, calcium rate, conduct ultrasound examination of the neck and retroperitoneal space.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Feocromocitoma
/
Neoplasias de la Tiroides
/
Neoplasias de las Glándulas Suprarrenales
/
Neoplasia Endocrina Múltiple Tipo 2a
/
Hiperparatiroidismo
/
Hipertensión
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Uk
Revista:
Klin Khir
Año:
2012
Tipo del documento:
Article
Pais de publicación:
Ucrania