Transient hypothermia and hyperphagia induced by selenium and tellurium compounds in mice.
Toxicol Lett
; 50(2-3): 319-26, 1990 Feb.
Article
en En
| MEDLINE
| ID: mdl-2309249
The effects of sublethal doses of selenite, selenate, selenocystine (Se-Cys) and selenomethionine (Se-Met) as well as of tellurite on body temperature and feeding behavior were examined in male ICR mice. Ten or 30 mumol/kg of chemicals were injected subcutaneously and body temperature was measured up to 4 h. In a separate experiment, the gastric content was weighted 4 h after injection. All chemicals except Se-Met induced both hypothermia and hyperphagia, suggesting that: (a) these two effects are related to each other; (b) among the chemicals tested, Se-Cys appears to be the most potent hypothermia inducer; (c) Se-Met is unique in that it has neither effect.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Selenio
/
Telurio
/
Hiperfagia
/
Compuestos de Organoselenio
/
Compuestos de Selenio
/
Hipotermia
Límite:
Animals
Idioma:
En
Revista:
Toxicol Lett
Año:
1990
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Países Bajos