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Multiple pathways carry signals from short-wavelength-sensitive ('blue') cones to the middle temporal area of the macaque.
Jayakumar, Jaikishan; Roy, Sujata; Dreher, Bogdan; Martin, Paul R; Vidyasagar, Trichur R.
Afiliación
  • Jayakumar J; Department of Optometry and Vision Sciences, The University of Melbourne, Parkville VIC 3010, Australia.
J Physiol ; 591(1): 339-52, 2013 Jan 01.
Article en En | MEDLINE | ID: mdl-23070701
We recorded spike activity of single neurones in the middle temporal visual cortical area (MT or V5) of anaesthetised macaque monkeys. We used flashing, stationary spatially circumscribed, cone-isolating and luminance-modulated stimuli of uniform fields to assess the effects of signals originating from the long-, medium- or short- (S) wavelength-sensitive cone classes. Nearly half (41/86) of the tested MT neurones responded reliably to S-cone-isolating stimuli. Response amplitude in the majority of the neurones tested further (19/28) was significantly reduced, though not always completely abolished, during reversible inactivation of visuotopically corresponding regions of the ipsilateral primary visual cortex (striate cortex, area V1). Thus, the present data indicate that signals originating in S-cones reach area MT, either via V1 or via a pathway that does not go through area V1. We did not find a significant difference between the mean latencies of spike responses of MT neurones to signals that bypass V1 and those that do not; the considerable overlap we observed precludes the use of spike-response latency as a criterion to define the routes through which the signals reach MT.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Visual / Células Fotorreceptoras Retinianas Conos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Physiol Año: 2013 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Visual / Células Fotorreceptoras Retinianas Conos Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: J Physiol Año: 2013 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido