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Learning of new sound categories shapes neural response patterns in human auditory cortex.
Ley, Anke; Vroomen, Jean; Hausfeld, Lars; Valente, Giancarlo; De Weerd, Peter; Formisano, Elia.
Afiliación
  • Ley A; Department of Medical Psychology and Neuropsychology, Tilburg University, 5037 AB Tilburg, The Netherlands. anke.ley@maastrichtuniversity.nl
J Neurosci ; 32(38): 13273-80, 2012 Sep 19.
Article en En | MEDLINE | ID: mdl-22993443
The formation of new sound categories is fundamental to everyday goal-directed behavior. Categorization requires the abstraction of discrete classes from continuous physical features as required by context and task. Electrophysiology in animals has shown that learning to categorize novel sounds alters their spatiotemporal neural representation at the level of early auditory cortex. However, functional magnetic resonance imaging (fMRI) studies so far did not yield insight into the effects of category learning on sound representations in human auditory cortex. This may be due to the use of overlearned speech-like categories and fMRI subtraction paradigms, leading to insufficient sensitivity to distinguish the responses to learning-induced, novel sound categories. Here, we used fMRI pattern analysis to investigate changes in human auditory cortical response patterns induced by category learning. We created complex novel sound categories and analyzed distributed activation patterns during passive listening to a sound continuum before and after category learning. We show that only after training, sound categories could be successfully decoded from early auditory areas and that learning-induced pattern changes were specific to the category-distinctive sound feature (i.e., pitch). Notably, the similarity between fMRI response patterns for the sound continuum mirrored the sigmoid shape of the behavioral category identification function. Our results indicate that perceptual representations of novel sound categories emerge from neural changes at early levels of the human auditory processing hierarchy.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Auditiva / Percepción Auditiva / Sonido / Mapeo Encefálico / Aprendizaje Límite: Adult / Female / Humans / Male Idioma: En Revista: J Neurosci Año: 2012 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Corteza Auditiva / Percepción Auditiva / Sonido / Mapeo Encefálico / Aprendizaje Límite: Adult / Female / Humans / Male Idioma: En Revista: J Neurosci Año: 2012 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Estados Unidos