Noninvasive evaluation of the chronic influence of local air velocity from an air conditioner using salivary cortisol and skin caspase-14 as biomarkers of psychosomatic and environmental stress.
J Int Med Res
; 40(4): 1429-37, 2012.
Article
en En
| MEDLINE
| ID: mdl-22971494
OBJECTIVE: To demonstrate the possibility of evaluating the chronic influence of local air velocity from an air conditioner using noninvasive biomarkers. METHODS: Over a consecutive 5-day period, 16 healthy young male adults were exposed to air flow from a whole ceiling-type air conditioner (low local air velocity) and from a commercial concentrated exhaust air conditioner (high local air velocity). Salivary cortisol was used as an index of the psychological effects and caspase-14, collected from the stratum corneum, was used as a marker of environmental stress on the skin. RESULTS: Local air velocity generated from the whole ceiling-type air conditioner where the subject's head was positioned was one-seventh that of the exhaust air conditioner. After exposure to the exhaust air conditioner for 5 days, salivary cortisol decreased significantly from morning to evening and skin caspase-14 gradually increased during the day. A significant increase in hydration index from the morning to the evening was found with the whole ceiling-type air conditioner. CONCLUSION: The effects of chronic exposure to air movement generated by an air conditioner may be quantified by measurement of salivary cortisol and skin caspase-14.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saliva
/
Piel
/
Estrés Psicológico
/
Hidrocortisona
/
Caspasas
/
Aire Acondicionado
/
Exposición a Riesgos Ambientales
Tipo de estudio:
Clinical_trials
/
Etiology_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
J Int Med Res
Año:
2012
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Reino Unido