Allogeneic hematopoietic stem cell transplantation (HSCT) for high-risk acute myeloid leukemia (AML)/myelodysplastic syndrome (MDS): how can we improve outcomes in the near future?
Leuk Res
; 36(12): 1490-5, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-22954609
Substantive advances in the past decade or so have allowed for a wider spectrum of patients to undergo allo-HSCT and have increased its safety, thus broadening the application of this therapy[36]. That said, disease persistence or (more commonly) recurrence remains as primary problems. A combination of "extrinsic" and "intrinsic" methods is now available and ready for additional clinical testing and/or utilization. Fortunately, one can be somewhat optimistic that better results will be achieved, perhaps very soon. However, and as these strategies and techniques are evaluated, it should be realized that some may be too complex and/or expensive for widespread use as the need to reduce costs becomes more pressing.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndromes Mielodisplásicos
/
Leucemia Mieloide Aguda
/
Trasplante de Células Madre Hematopoyéticas
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
Leuk Res
Año:
2012
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Reino Unido