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[Distortion of the pressor response to adrenaline in hepatectomized and tumor-bearing rats]. / Izvrashchenie pressornoi reaktsii na adrenalin u gepatéktomirovannykh krys i u zhivotnykh-opukholenositelei.
Patol Fiziol Eksp Ter ; (5): 19-21, 1990.
Article en Ru | MEDLINE | ID: mdl-2293153
Similar distortion of hypertensive response to epinephrine occurred in sarcoma-45-bearing rats, Walker carcinosarcoma-bearing rats, and hepatectomized rats. The response in the last-named was distorted on the 3rd postoperative day. The hypertensive response to epinephrine was restored after the regenerative processes in the liver were completed (7th-10th postoperative day). Distortion of the response in carcinosarcoma-bearing rats was detected beginning from the 4th day after transplantation in some of the animals and on the 14th day in the others; in all sarcoma 45-bearing rats distortion occurred by the 20th day. The pressor response was distorted usually under conditions of pharmacological block of the alpha-adrenergic receptors. It is assumed that in extensive proliferation of normal and neoplastic cells, substances exerting a selective blocking effect on the alpha-adrenoceptors of the blood vessels penetrate into circulation.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoma Experimental / Presión Sanguínea / Carcinoma 256 de Walker / Epinefrina / Hígado Límite: Animals Idioma: Ru Revista: Patol Fiziol Eksp Ter Año: 1990 Tipo del documento: Article Pais de publicación: Rusia
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoma Experimental / Presión Sanguínea / Carcinoma 256 de Walker / Epinefrina / Hígado Límite: Animals Idioma: Ru Revista: Patol Fiziol Eksp Ter Año: 1990 Tipo del documento: Article Pais de publicación: Rusia