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An appeal for the presentation of detailed human derived data for dose-response calculations in nutritional science.
de Jong, Nynke; Verkaik-Kloosterman, Janneke; Verhagen, Hans; Boshuizen, Hendriek C; Bokkers, Bas; Hoekstra, Jeljer.
Afiliación
  • de Jong N; National Institute for Public Health and The Environment, Bilthoven, The Netherlands.
Food Chem Toxicol ; 54: 43-9, 2013 Apr.
Article en En | MEDLINE | ID: mdl-22902968
If a diet, food or food constituent is recognised to have both health benefits and health risks, the benefits have to be compared with the risks to develop coherent scientific evidence-based dietary advice. This means that both risk and benefit assessment should follow a similar paradigm and that benefits and risks are expressed in a common currency. Dose-response functions are vital for that purpose. However, the construction of these functions is often of second interest in the currently available (epidemiological) literature. In order to bring forward the potential of epidemiological studies for the construction of the dose-response functions for benefit-risk purposes, the scientific (nutrition and health) community is asked to expand on their data presentation, either by presenting more detailed data focusing on dose-response necessities, and/or by sharing primary data.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Relación Dosis-Respuesta a Droga / Ciencias de la Nutrición Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Food Chem Toxicol Año: 2013 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Relación Dosis-Respuesta a Droga / Ciencias de la Nutrición Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Food Chem Toxicol Año: 2013 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido