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[Antioxidant status after surgical stress]. / Untersuchungen zum Antioxidantienstatus nach operativem Stress.
Kreinhoff, U; Elmadfa, I; Salomon, F; Weidler, B.
Afiliación
  • Kreinhoff U; Institut für Ernährungswissenschaft, Universität Giessen.
Infusionstherapie ; 17(5): 261-7, 1990 Oct.
Article en De | MEDLINE | ID: mdl-2289819
Trauma and anaesthetics are responsible for local and general change in the organism. The characteristic changes in metabolism are caused by hormones. In addition, the increased glycogenolysis, gluconeogenesis, proteolysis and lipolysis are characteristic of this catabolic metabolism. Three groups (injured patients, patients with pulmonary disease, multiple trauma patients) showed an elevated lipid peroxidation as indicated by increased formation of TBA-reactive substances in the post-trauma or after surgery phase. The production of free radicals is supported by several stress factors. In this connection, the state of metabolism of the patients, several anaesthetics and the artificial respiration is very important. Enzymatic protecting systems (SOD, GSH-Px, Catalase) react to oxidative stress by positive adaptation. The non-enzymatic antioxidative systems (tocopherol, ascorbic acid, selen) are diminished, indicating an increased requirement.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Heridas y Lesiones / Traumatismo Múltiple / Peroxidación de Lípido / Neoplasias Pulmonares Límite: Humans / Male Idioma: De Revista: Infusionstherapie Asunto de la revista: CIENCIAS DA NUTRICAO Año: 1990 Tipo del documento: Article Pais de publicación: Suiza
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Heridas y Lesiones / Traumatismo Múltiple / Peroxidación de Lípido / Neoplasias Pulmonares Límite: Humans / Male Idioma: De Revista: Infusionstherapie Asunto de la revista: CIENCIAS DA NUTRICAO Año: 1990 Tipo del documento: Article Pais de publicación: Suiza