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Quantifying optical microangiography images obtained from a spectral domain optical coherence tomography system.
Reif, Roberto; Qin, Jia; An, Lin; Zhi, Zhongwei; Dziennis, Suzan; Wang, Ruikang.
Afiliación
  • Reif R; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Int J Biomed Imaging ; 2012: 509783, 2012.
Article en En | MEDLINE | ID: mdl-22792084
The blood vessel morphology is known to correlate with several diseases, such as cancer, and is important for describing several tissue physiological processes, like angiogenesis. Therefore, a quantitative method for characterizing the angiography obtained from medical images would have several clinical applications. Optical microangiography (OMAG) is a method for obtaining three-dimensional images of blood vessels within a volume of tissue. In this study we propose to quantify OMAG images obtained with a spectral domain optical coherence tomography system. A technique for determining three measureable parameters (the fractal dimension, the vessel length fraction, and the vessel area density) is proposed and validated. Finally, the repeatability for acquiring OMAG images is determined, and a new method for analyzing small areas from these images is proposed.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Biomed Imaging Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Biomed Imaging Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos