Apathy syndrome treated successfully with modafinil.
BMJ Case Rep
; 20112011 Nov 15.
Article
en En
| MEDLINE
| ID: mdl-22674596
The treatment of apathy is often complicated and difficult. The authors present a case of apathy syndrome that was treated successfully with modafinil. An 87-year-old widowed Brazilian woman presented with loss of interest and pleasure in activities. Her level of apathy, as evaluated by the Brazilian care giver version of the apathy scale, was 25 (a score higher than 18 points is associated with an apathy syndrome). No diagnosis of depression or sleep disorder was noted. After 2 years with many different antidepressants, modafinil treatment was started at 100 mg/day. One month after the initiation of modafinil therapy, the patient reported feeling more motivation, and she also returned to her favorite physical activity, which was swimming (400 m/day). Apathy scale revealed an improvement (18 points). Actigraphic analysis was performed, and no sleep disturbances were noted before or after treatment. Modafinil may be a promising option in the treatment of apathy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos de Bencidrilo
/
Síntomas Afectivos
/
Apatía
/
Estimulantes del Sistema Nervioso Central
Límite:
Aged80
/
Female
/
Humans
Idioma:
En
Revista:
BMJ Case Rep
Año:
2011
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Reino Unido