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A method for monitoring antibodies against staphylococcal DNases.
Høie, S; Gudding, R.
Afiliación
  • Høie S; Department of Microbiology and Immunology, Norwegian College of Veterinary Medicine, Oslo.
Acta Vet Scand ; 31(2): 223-6, 1990.
Article en En | MEDLINE | ID: mdl-2260516
When small amounts of DNase produced by Staphylococcus aureus, S. intermedius or S. hyicus were added to Toluidine Blue DNA Agar (TDA), a medium for demonstration of staphylococcal antiDNases was produced. By applying this medium in microtitre plates, a test system for titration of staphylococcal antibodies in serum samples was developed. A colour change from blue to pink could be observed when the DNase was allowed to act, i.e. when no staphylococcal antiDNases were present in the samples. When serum with neutralizing antibodies were applied, no colour change developed. An end-point could easily be demonstrated in dilutions of the serum. A description of the method, including certain of its limitations is given.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus / Desoxirribonucleasas / Nucleasa Microcócica / Anticuerpos Antibacterianos Límite: Animals Idioma: En Revista: Acta Vet Scand Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Staphylococcus / Desoxirribonucleasas / Nucleasa Microcócica / Anticuerpos Antibacterianos Límite: Animals Idioma: En Revista: Acta Vet Scand Año: 1990 Tipo del documento: Article Pais de publicación: Reino Unido