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Two-photon laser polymerization: from fundamentals to biomedical application in tissue engineering and regenerative medicine.
Raimondi, Manuela T; Eaton, Shane M; Nava, Michele M; Laganà, Matteo; Cerullo, Giulio; Osellame, Roberto.
Afiliación
  • Raimondi MT; LaBS, Department of Structural Engineering, Politecnico di Milano, Milano, Italy. manuela.raimondi@polimi.it
J Appl Biomater Funct Mater ; 10(1): 55-65, 2012 Jun 26.
Article en En | MEDLINE | ID: mdl-22562455
Three-dimensional material microstructuring by femtosecond laser-induced two-photon polymerization is emerging as an important tool in biomedicine. During two-photon polymerization, a tightly focused femtosecond laser pulse induces a crosslinking photoreaction in the polymer confined within the focal volume. As a rapid-prototyping technique, two-photon polymerization enables the fabrication of truly arbitrary three-dimensional micro- and nano-structures directly from computer models, with a spatial resolution down to 100 nm. In this review, we discuss the fundamentals, experimental methods, and materials used for two-photon polymerization; in addition, we present some applications of this technology related to microfluidics and to biomaterial scaffolds for tissue engineering and regenerative medicine.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Materiales Biocompatibles / Fotones / Andamios del Tejido / Polimerizacion / Rayos Láser Límite: Animals / Humans Idioma: En Revista: J Appl Biomater Funct Mater Año: 2012 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Materiales Biocompatibles / Fotones / Andamios del Tejido / Polimerizacion / Rayos Láser Límite: Animals / Humans Idioma: En Revista: J Appl Biomater Funct Mater Año: 2012 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos