The purple toe syndrome in female with Factor V Leiden mutation successfully treated with enoxaparin.
Clin Appl Thromb Hemost
; 19(1): 100-2, 2013.
Article
en En
| MEDLINE
| ID: mdl-22531482
Purple toe syndrome is a rare complication of warfarin therapy. It occurs usually after 3 to 8 weeks of therapy and it is caused by cholesterol emboli from atheromatous plaque. Sudden onset of pain in affected area, typically in toes and feet, is the main characteristic of the syndrome. We describe a case of a 65-year-old female with purple toe syndrome after 6 weeks of warfarin. Indication of warfarin was a proximal deep venous thrombosis, which developed after prolonged immobilization. Factor V (FV) Leiden and persistent high FVIII activity were found as additional eliciting factors for venous thromboembolism. After warfarin withdrawal and enoxaparin treatment, symptoms disappeared promptly but a slight discoloration of the toe persists.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Warfarina
/
Factor V
/
Dedos del Pie
/
Enoxaparina
/
Embolia por Colesterol
/
Fibrinolíticos
/
Anticoagulantes
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Clin Appl Thromb Hemost
Asunto de la revista:
ANGIOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
República Checa
Pais de publicación:
Estados Unidos