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Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.
Fisher, Nicholas; Abd Majid, Roslaini; Antoine, Thomas; Al-Helal, Mohammed; Warman, Ashley J; Johnson, David J; Lawrenson, Alexandre S; Ranson, Hilary; O'Neill, Paul M; Ward, Stephen A; Biagini, Giancarlo A.
Afiliación
  • Fisher N; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Abd Majid R; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Antoine T; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Al-Helal M; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Warman AJ; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Johnson DJ; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • Lawrenson AS; Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom.
  • Ranson H; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and.
  • O'Neill PM; Department of Chemistry, University of Liverpool, Liverpool L69 7ZD, United Kingdom.
  • Ward SA; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and. Electronic address: saward@liv.ac.uk.
  • Biagini GA; Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom and. Electronic address: Biagini@liverpool.ac.uk.
J Biol Chem ; 287(13): 9731-9741, 2012 Mar 23.
Article en En | MEDLINE | ID: mdl-22282497
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Regulación Enzimológica de la Expresión Génica / Proteínas Protozoarias / Mutación Missense / Citocromos b / Atovacuona / Antimaláricos Límite: Humans Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plasmodium falciparum / Resistencia a Medicamentos / Regulación Enzimológica de la Expresión Génica / Proteínas Protozoarias / Mutación Missense / Citocromos b / Atovacuona / Antimaláricos Límite: Humans Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article Pais de publicación: Estados Unidos