A review on mucoadhesive polymer used in nasal drug delivery system.
J Adv Pharm Technol Res
; 2(4): 215-22, 2011 Oct.
Article
en En
| MEDLINE
| ID: mdl-22247888
This update review is on mucoadhesive polymers used in nasal dosage forms. The nasal mucosa provides a potentially good route for systemic drug delivery. One of the most important features of the nasal route is that it avoids first-pass hepatic metabolism, thereby reducing metabolism. The application of mucoadhesive polymers in nasal drug delivery systems has gained to promote dosage form residence time in the nasal cavity as well as improving intimacy of contact with absorptive membranes of the biological system. The various new technology uses in development of nasal drug delivery dosage forms are discussed. The various dosage forms are vesicular carriers (liposome, noisome), nanostructured particles, prodrugs, in situ gelling system with special attention to in vivo studies.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Adv Pharm Technol Res
Año:
2011
Tipo del documento:
Article
País de afiliación:
India
Pais de publicación:
India