Sarcoidosis manifesting as cardiac sarcoidosis and massive splenomegaly.

Kawano, Sayaka; Kato, Johji; Kawano, Noriaki; Yoshimura, Yuki; Masuyama, Hiroyuki; Fukunaga, Takashi; Shimao, Yoshiya; Mihara, Kenroh; Ueda, Akira; Toyoda, Kiyokazu; Imamura, Takuroh; Kitamura, Kazuo

Kawano, Sayaka; Kato, Johji; Kawano, Noriaki; Yoshimura, Yuki; Masuyama, Hiroyuki; Fukunaga, Takashi; Shimao, Yoshiya; Mihara, Kenroh; Ueda, Akira; Toyoda, Kiyokazu; Imamura, Takuroh; Kitamura, Kazuo.

Afiliación

Kawano S; Department of Internal Medicine, Circulatory and Body Fluid Regulation, Faculty of Medicine, University of Miyazaki, Japan. sayakawano23@yahoo.co.jp

Intern Med ; 51(1): 65-9, 2012.

Article en En | MEDLINE | ID: mdl-22214625

RESUMEN

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. We report an unusual case of sarcoidosis in a woman presenting with cardiac sarcoidosis and massive splenomegaly with a familial history of cardiac sarcoidosis. Cardiac sarcoidosis was diagnosed based on electrocardiogram, echocardiogram, 18F-fluoro-2-deoxyglucose positron emission tomography (18F-FDG-PET) and skin histological findings. We performed splenectomy to rule out malignant lymphoma, and histological findings confirmed sarcoidosis. After splenectomy, we initiated prednisolone therapy. After 20 months of diagnosis, she was symptom free. Echocardiography and 18F-FDG-PET may be a key diagnostic tool and prednisolone therapy may be safe, effective, and feasible for cardiac sarcoidosis.

Asunto(s)

Cardiomiopatías/diagnóstico; Sarcoidosis/diagnóstico; Esplenomegalia/etiología; Cardiomiopatías/complicaciones; Cardiomiopatías/diagnóstico por imagen; Ecocardiografía; Electrocardiografía; Femenino; Fluorodesoxiglucosa F18; Humanos; Persona de Mediana Edad; Tomografía de Emisión de Positrones; Radiofármacos; Sarcoidosis/complicaciones; Sarcoidosis/diagnóstico por imagen; Esplenomegalia/diagnóstico; Esplenomegalia/diagnóstico por imagen

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sarcoidosis / Esplenomegalia / Cardiomiopatías Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Intern Med Asunto de la revista: MEDICINA INTERNA Año: 2012 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón

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