The association between morning cortisol and adiposity in children varies by weight status.
J Pediatr Endocrinol Metab
; 24(9-10): 709-13, 2011.
Article
en En
| MEDLINE
| ID: mdl-22145461
OBJECTIVE: To examine the associations between morning cortisol and adiposity in children at baseline and 9-month follow-up. METHODS: Participants included 649 (301 males, 348 females) children (9.6 +/- 0.9 years) for the cross-sectional analysis and 316 (153 males, 163 females) for the longitudinal analysis. Body mass index (BMI, kg/m2) was calculated from measured height and weight and waist circumference (WC, cm) was measured at the superior border of the iliac crest. Cortisol was assessed via saliva samples collected on a single morning. Cross-sectional and longitudinal analyses were conducted to examine the relationships between cortisol and adiposity. RESULTS: Approximately 31% were overweight (17.7%) or obese (12.8%). The mean cortisol level was 9.36 +/- 5.64 nmol/L (0.34 +/- 0.20 microg/dL). At baseline, no significant correlations were found between cortisol and BMI or WC (r < 0.07). Baseline cortisol did not correlate with change in BMI z-score (r = -0.03) or WC (r < -0.01) over the follow-up period. When examined by weight status, baseline cortisol was significantly related to changes in WC (r = 0.32) and BMI z-score (r = 0.28) among overweight subjects. CONCLUSIONS: A positive relationship was found between morning cortisol and change in WC over 9 months in overweight children. Future studies should examine the association between 24-h cortisol patterns and direct measures of trunk fat.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peso Corporal
/
Hidrocortisona
/
Ritmo Circadiano
/
Adiposidad
/
Obesidad
Tipo de estudio:
Risk_factors_studies
Límite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Pediatr Endocrinol Metab
Asunto de la revista:
ENDOCRINOLOGIA
/
PEDIATRIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Alemania