Transmission of tick-borne pathogens between co-feeding ticks: Milan Labuda's enduring paradigm.
Ticks Tick Borne Dis
; 2(4): 179-82, 2011 Dec.
Article
en En
| MEDLINE
| ID: mdl-22108009
During the 1990s, Milan Labuda's experimental results established a new paradigm for the study of tick-borne viruses that has since been strengthened by its demonstrated effectiveness in explaining the epidemiology of tick-borne encephalitis (TBE). This brief review summarizes the essential features of the transmission of tick-borne pathogens such as TBE virus. Leukocytes migrate between tick feeding sites, bearing infective virions and providing a transport route for the virus between co-feeding ticks independent of a systemic viraemia. Such tick-borne pathogens are thus transmitted from tick to tick via vertebrates; the ticks are the reservoirs as well as the vectors, while the vertebrate is the transient bridge. The aim is to bring the related but non-synonymous terms (co-feeding and non-systemic) to the attention of workers who use simple PCR screening to identify additional vertebrate reservoir hosts of vector-borne pathogens that are not in fact maintained in nature through systemic transmission.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vectores Arácnidos
/
Infestaciones por Garrapatas
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Garrapatas
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Vertebrados
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Encefalitis Transmitida por Garrapatas
/
Virus de la Encefalitis Transmitidos por Garrapatas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Ticks Tick Borne Dis
Año:
2011
Tipo del documento:
Article
Pais de publicación:
Países Bajos