[Use of cyanoacrylate in the endoscopic therapy of gastric varices: experience in the National Hospital Edgardo Rebagliati Martins from 2006 to 2010]. / Uso de cianoacrilato en la terapia endoscópica de várices gástricas: experiencia en el Hospital Nacional Edgardo Rebagliati Martins del 2006 al 2010.
Rev Gastroenterol Peru
; 31(3): 208-15, 2011.
Article
en Es
| MEDLINE
| ID: mdl-22086314
OBJECTIVE: To evaluate the therapeutic success of the injection of N-butyl-2 cyanoacrylate in the treatment of gastric varices. METHODS: Cross-sectional study included 33 patients with gastric varices who only received cyanoacrylate endoscopic therapy between 2006 and 2010. Intravariceally, cyanoacrylate was injected in a 1:1 dilution with lipiodol until the obliteration of varices. The therapeutic situation was: active bleeding, varices with stigmata of recent bleeding and secondary prophylaxis. Treatment success was evaluated according to hemostasis, recurrent bleeding and obliteration. RESULTS: Of the 33 patients, 3 (9.1%) were for active bleeding, 20 (60.6%) with stigmata of recent bleeding and 10 (30.3%) as secondary prophylaxis. Gastric varices were GOV2, 17 (51.5%); IGV1, 14 (42.4%); GOV1, 2 (6.1%). Hemostasis was achieved in 21 (91.3%) and in 2 (66.7%) of 3 patients with active bleeding. Five (15.6%) patients had recurrent bleeding and 2 of them used cyanoacrylate with successful hemostasis. Obliteration was achieved. Four patients died and one for failure of control bleeding. A high severity of Child-Pugh classification was related to treatment endoscopic failure (p=0.034). The main complication was bleeding after the injection of cyanoacrylate. CONCLUSIONS: Our results support the use of cyanoacrylate in the treatment of gastric varices with few major complications.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Soluciones Esclerosantes
/
Várices Esofágicas y Gástricas
/
Escleroterapia
/
Gastroscopía
/
Hemostasis Endoscópica
/
Enbucrilato
/
Hemorragia Gastrointestinal
Tipo de estudio:
Evaluation_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Rev Gastroenterol Peru
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2011
Tipo del documento:
Article
Pais de publicación:
Perú