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Detection and analysis of proteins modified by O-linked N-acetylglucosamine.
Zachara, Natasha E; Vosseller, Keith; Hart, Gerald W.
Afiliación
  • Zachara NE; The Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Vosseller K; Drexel University College of Medicine, Philadelphia, Pennsylvania.
  • Hart GW; The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Curr Protoc Protein Sci ; Chapter 12: 12.8.1-12.8.33, 2011 Nov.
Article en En | MEDLINE | ID: mdl-22045558
O-GlcNAc is a common post-translational modification of nuclear, mitochondrial, and cytoplasmic proteins that is implicated in the etiology of type II diabetes and Alzheimer's disease, as well as cardioprotection. This unit covers simple and comprehensive techniques for identifying proteins modified by O-GlcNAc, studying the enzymes that add and remove O-GlcNAc, and mapping O-GlcNAc modification sites.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilglucosamina / Proteínas Tipo de estudio: Diagnostic_studies Idioma: En Revista: Curr Protoc Protein Sci Año: 2011 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetilglucosamina / Proteínas Tipo de estudio: Diagnostic_studies Idioma: En Revista: Curr Protoc Protein Sci Año: 2011 Tipo del documento: Article Pais de publicación: Estados Unidos