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An expert consortium review of the EC-commissioned report "alternative (Non-Animal) methods for cosmetics testing: current status and future prospects - 2010".
Hartung, Thomas; Blaauboer, Bas J; Bosgra, Sieto; Carney, Edward; Coenen, Joachim; Conolly, Rory B; Corsini, Emanuela; Green, Sidney; Faustman, Elaine M; Gaspari, Anthony; Hayashi, Makoto; Wallace Hayes, A; Hengstler, Jan G; Knudsen, Lisbeth E; Knudsen, Thomas B; McKim, James M; Pfaller, Walter; Roggen, Erwin L.
Afiliación
  • Hartung T; Johns Hopkins University, Bloomberg School of Public Health, Center for Alternatives to Animal Testing, Baltimore, MD 21205, USA. THartung@jhsph.edu
ALTEX ; 28(3): 183-209, 2011.
Article en En | MEDLINE | ID: mdl-21993956
The European cosmetics legislation foresees a review in 2011 and possible postponement of the 2013 marketing ban to enforce the testing ban for systemic and repeated-dose animal tests. For this purpose, a 119-page report commissioned by the European Commission was published recently. Here, a group of 17 independent experts from the US, Europe, and Japan was brought together to evaluate the report. The expert panel strongly endorsed the report and its conclusions. A number of important options not considered were identified; these do not, however, affect the overall conclusions regarding the current lack of availability of a full replacement, especially for the areas of repeated dose toxicity, carcinogenicity testing, and reproductive toxicity, though a roadmap for change is emerging. However, some of these options may provide adequate data for replacement of some animal studies in the near future pending validation. Various recommendations expand the original report. The reviewers agree with the report that there is greater promise in the short term for the areas of sensitization and toxicokinetics. Additional opportunities lie in more global collaborations and the inclusion of other industry sectors.
Asunto(s)
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Toxicidad / Cosméticos / Alternativas a las Pruebas en Animales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: ALTEX Asunto de la revista: MEDICINA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pruebas de Toxicidad / Cosméticos / Alternativas a las Pruebas en Animales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: ALTEX Asunto de la revista: MEDICINA Año: 2011 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania