[Immunologic aging. Effect of denutrition]. / Le viellissement immunologique. Influence de la dénutrition.
Ann Biol Clin (Paris)
; 48(5): 309-18, 1990.
Article
en Fr
| MEDLINE
| ID: mdl-2195926
Ageing leads to decrease of immune functions. The T lymphocyte is more susceptible to ageing than the B lymphocyte for which in vitro functions are almost preserved. All functions of cell mediated immunity are decreased in elderly. T lymphocyte are less mature, present decreased T helper and T suppressive functions, decreased T proliferative ability responses to stimuli and lower interleukin synthesis. T dependent antibody responses are also decreased: primary responses are diminished and secondary responses less specific. Nevertheless in healthy elderly such immune deficiency remains minor. Underdiminution whatever it concerns (mostly proteins but also vitamin or trace elements) also leads to immunodeficiency. When it occurs in aged individuals, undernutrition rapidly induces a profound immunodeficit. Prevention of prompt treatment of all undernutrition states is a major concern in geriatrics.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Trastornos Nutricionales
Límite:
Aged
/
Aged80
/
Humans
Idioma:
Fr
Revista:
Ann Biol Clin (Paris)
Año:
1990
Tipo del documento:
Article
Pais de publicación:
Francia